Here is a report on a Microsoft expansion of something called FLS slots, which have something to do with threads, in the Windows 10 kernel specifically in order to accommodate DAW users desire to load multiple plug-ins. Previously, there has been a limit of 128 FLS slots, which some DAW users exhausted, and at some point this year they plan to up that to '...just over 4,000' (4096?). Until now, when you ran up against the limit, the plug-in would just refuse to load. The update is supposed to happen to W10 automatically at some point and probably without announcement. There's a whole explanation of the issue and what the expansion means here:

https://www.kvraudio.com/forum/viewtopic.php?p=7281357

It has been a serious enough issue for some people that someone has even written a utility to check the number of free FLS slots yet available in one's system in realtime:

http://planetnine.jp/wp/2018/03/25/fls-checker/

Haven't tried it myself since I still do not use W10. But, for those that do...